WebThe granin family is thought to be one of the mediators of the regulated secretory pathway (2-6). This family is widely expressed in endocrine (7-9) and neuronal cells (10-12), where they are stored in secretory granules together with various peptide hormones and neuropeptides. Three acidic sulfated proteins, chromogranin A (Cg A ... WebDec 20, 2024 · CgA was the first of the eight members of the granin family to be identified. Granins are the major components of the soluble core of dense-core secretory granules in NE cells and are, therefore, secreted by these cells. Additionally, granins are thought to play important roles in granulogenesis, ...
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WebCgA is a 49kDa glycoprotein of 439 amino acids, belonging to the granin family of regulated secretory proteins identified in secretory granules throughout the neuroendocrine system and in a variety of neurons, both central and peripheral ( 131 ). WebMar 6, 2024 · CgA is a heat-stable, 439-amino acid protein, and a member of the granin family of proteins. Granins are widespread in endocrine, neuroendocrine, peripheral, and central nervous tissues, where they are … how big is the burren
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Granin (chromogranin and secretogranin) is a protein family of regulated secretory proteins ubiquitously found in the cores of amine and peptide hormone and neurotransmitter dense-core secretory vesicles. See more Granins (chromogranins or secretogranins) are acidic proteins and are present in the secretory granules of a wide variety of endocrine and neuro-endocrine cells. The exact function(s) of these proteins is not yet … See more Apart from their subcellular location and the abundance of acidic residues (Asp and Glu), these proteins do not share many structural similarities. Only one short region, located in the C-terminal section, is conserved in all these proteins. Chromogranins and … See more • Chromogranins at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more WebApr 3, 2024 · Grandin is a scientist, author, and professor of animal science at Colorado State University. Grandin didn’t have an easy start to life. She was diagnosed with autism when she was three, ostracized by her peers, and socially isolated. She joined us on the Science of Happiness podcast to talk about those who supported her along the way to ... WebAleksandr Leonovitch Granin (Russian: Александр Леонович Гранин) was a Soviet weapons scientist, the former director of the OKB-812 Granin Design Bureau, and the creator of the Metal Gear concept. Granin was … how big is the business travel market