Hif1a分子量
Web9 de jul. de 2024 · Background: Hypoxia-inducible factor 1α (HIF1A), the principal regulator of hypoxia, is involved in the suppression of antitumor immunity. We aimed to describe the T-cell exhaustion status of gliomas under different levels of HIF1A expression.Methods: In this study, 692 patients, whose data were collected from the Chinese Glioma Genome … Web25 de mar. de 2024 · We obtained femoral heads from Col2a1-Cre ERT2; Hif1a fl/fl (KO) and Hif1a fl/fl (Cntl) mice after tamoxifen treatment, and cultured them with or without IL …
Hif1a分子量
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WebHIF1A(Hypoxia-inducible factor 1-alpha)是由 826 个氨基酸组成的大小为 90.6KD 蛋白质。 HIF1A亚基由bHLH结构域、PAS结构域、ODD结构域以及反式激活结构域四部分共同组 … Web26 de fev. de 2024 · The competence of tumor cells to endure oxygen depletion is largely due to accumulation of Hypoxia-inducible factor 1 (HIF-1), a transcription factor consisting of an O 2 -responsive HIF-1α subunit...
Web31 de mai. de 2013 · 呵呵,前段时间也一直在纠结这个蛋白的wb,最近两天用HepG2细胞经过CoCl2处理以后发现结果还行,就是有个问题,低浓度的Cocl2处理Hif1a多,比control多不少,而高浓度处理24小时反而一点都没有了,奇怪。 Web9 de dez. de 2024 · The transcription factor HIF1A is a canonical master-regulator of hypoxic signaling, translocating to the nucleus under hypoxic conditions and regulating multiple pathways, including angiogenesis...
WebHIF-1α Antibody (28b) is an IgG 1 κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the detection of the HIF … Web28 de dez. de 2016 · Background Obstructive sleep apnea (OSA) is associated with the progression of non-alcoholic fatty liver disease (NAFLD) to steatohepatitis and fibrosis. This progression correlates with the severity of OSA-associated hypoxia. In mice with diet induced obesity, hepatic steatosis leads to liver tissue hypoxia, which worsens with …
Web17 de ago. de 2024 · Both HIF-1α and HIF-2α are required for the clear cell phenotype. Transcriptomic and proteomic analyses reveal that HIF-1α regulates glycolysis while HIF-2α regulates genes associated with lipoprotein metabolism, ribosome biogenesis and E2F and MYC transcriptional activities.
WebHIF1A antibody; HIF1A_HUMAN antibody; hifla antibody; Hypoxia inducible factor 1 alpha antibody; Hypoxia inducible factor 1 alpha isoform I.3 antibody; Hypoxia inducible factor … birthday present for auntieWeb15 de nov. de 2024 · HIF1A-deficient cancer cells express a proinflammatory signature that is dependent on glycogen In order to explore the mechanism by which increased glycogen accumulation could contribute to HIF1A-independent tumor growth, we analyzed the signaling pathways upregulated in shHIF1A cells. danskin now plus size activewearWeb1 de set. de 2010 · Our recent studies have mechanistically implicated a loss of stromal Cav-1 expression and HIF1-alpha-activation in driving the cancer-associated fibroblast phenotype, through the paracrine production of nutrients … danskin now racerback active shirtsWeb腫瘍細胞の低酸素応答研究に有用 HIF1α 抗体. HIF1a 抗体(anti HIF1a antibody)は、HIF1a タンパク質を検出するウサギポリクローナル抗体です。. 低酸素条件下で誘導される転写因子である HIF1α を検出します。. danskin now plus size dri core relaxed pantsWeb21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, … danskin now pants fittedWeb26 de jul. de 2016 · Background: Hyperthermia is a promising treatment for human lung cancer, but recurrence of the primary lesion is common, as the residual tumor becomes … danskin now racerback sports braWebHIF1A. Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the HIF1A gene. [5] [6] [7] The Nobel Prize in … birthday present for doctor