Phospho sting
WebPhospho-STING (Ser366) one-plate assay protocol Detection of Phosphorylated STING (Ser366) with HTRF reagents can be performed in a single plate used for culturing, … WebPhospho-STING-S365 Rabbit pAb (AP1199) Publication (1) Datasheet SDS Tested applications: WB Reactivity: Human, Mouse Western blot analysis of extracts of THP-1 cells, using Phospho-STING-S365 antibody (AP1199) at 1:1000 dilution.THP-1 cells were treated by PMA (80 nM) at 37℃ for overnight.
Phospho sting
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WebSTING activation in patient tumors and in platinum-treated preclinical NSCLC models was correlated with biomarkers of immunotherapy response. Results: STING activation is associated with higher levels of intrinsic DNA damage, targetable immune checkpoints, and chemokines in treatment-naive and relapsed lung adenocarcinoma. WebDescription Rabbit monoclonal [SP338] to STING Host species Rabbit Tested applications Suitable for: IHC-P, Flow Cyt, WB, ICC/IF more details Species reactivity Reacts with: Rat, …
WebPhospho-STING (Ser365) Antibody (PA5-117271) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser365) Polyclonal Antibody (Product # PA5-117271). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Product Details WebJan 13, 2024 · STING (stimulator of interferon genes) is an important innate immune protein, but its homeostatic regulation at the resting state is unknown. Here, we identified TOLLIP as a stabilizer of STING...
WebInterestingly, we found that STING interacts with both TBK1 and IRF3, and that mutations in STING that selectively disrupt its binding to IRF3 abrogate IRF3 phosphorylation without impairing TBK1 activation. ... IRF3 also bound to phospho-TBK1 [TRAF family member-associated NFκB activator (TANK)-binding kinase] (Fig. 4 E and G), which is a ... WebPhospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species …
WebJun 7, 2024 · The assay showed the dependency of STING phosphorylation on the STING agonist, TBK1, “ER-to-Golgi” traffic, and palmitoylation, which mirrored the nature of …
sims 4 teen pregnancy cheatsWebInhibition of IDH3α enhanced the efficacy of chemoimmunotherapy by activating cGAS-STING pathway through regulating acidic tumor microenvironments. Preprint on Research Square on 11 October 2024 by Zhang, L., Dai, X., et al.. sims 4 teen pregnancy overhaulWebApr 8, 2024 · STING is composed of a short cytosolic N-terminal segment, a four-span transmembrane domain, a connector region and a cytosolic ligand-binding domain (LBD) … sims 4 teen pregnancy mod not workingWebCell Signaling Technology's Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) is a Rabbit monoclonal antibody. The Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) Antibody was generated using stimulator of interferon response cGAMP interactor 1, and STING1 as the antigen. It reacts with … sims 4 teen pregnancy mod 2023WebPhospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 488 Conjugate) #41622 Product Description. This Cell Signaling Technology antibody is conjugated to Alexa Fluor … sims 4 teen rags to riches challengeWebCell Signaling Technology Inc rabbit monoclonal anti human phospho sting ser366 d8k6h Rabbit Monoclonal Anti Human Phospho Sting Ser366 D8k6h, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more sims 4 teen relationshipsWebThe Mouse Phospho-STING (Ser365) assay measures mouse STING when phosphorylated at Ser365. Unlike Western Blot, the assay is entirely plate-based and does not require gels, … sims 4 teens can go to university mod