Pin proteins
WebAbout. I earned my PhD degree of biophysics at 2024 at UIUC. My PhD research focused on the application of fluorescence microscopy and innovative affinity probes to study protein of interests in ... WebJun 19, 2014 · PIN-FORMED (PIN) proteins are proposed auxin efflux transporters, and auxin fluxes can seemingly be predicted based on the—in many cells—asymmetric plasma membrane distribution of PINs.
Pin proteins
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In plants, the PIN proteins are integral membrane proteins that transport the anionic form of the phytohormone auxin across membranes. Most of the PIN proteins (e.g. PIN1/2/3/4/7 in the model plant Arabidopsis thaliana) localize at the plasma membrane (PM) where they serve as secondary active transporters involved in the efflux of auxin. The PM-localized PIN proteins show asymmetrical localisations on the membrane and are therefore responsible for polar auxin trans… WebMar 17, 2024 · The PIN proteins are fine-tuned at multiple levels, including transcriptional regulation, post-transcriptional modification, intracellular recycling and vacuolar trafficking for degradation, in response to endogenous and exogenous signals. Using genome-wide analysis, 12, 15 and 11 PIN like genes have been identified in rice, maize and sorghum ...
WebAlthough the detailed molecular mechanism of PIN proteins polarity establishment remains to be elucidated, many endogenous and exogenous regulators of PIN proteins … WebDec 1, 2014 · Results. We have found that treating gametophytic shoots of the moss Physcomitrella patens with exogenous auxins and auxin transport inhibitors disrupts apical function and leaf development. Two plasma membrane-targeted PIN proteins are expressed in leafy shoots, and pin mutants resemble plants treated with auxins or auxin …
WebJean-Philippe Pin got his PhD in Molecular Biology in 1987 at the University of Montpellier 2 (France). He participated in the discovery of the metabotropic glutamate receptors. As a post doctoral fellow at the Salk Institute, he cloned and characterized new mGlu receptor variants. In 1992, he joined Joel Bockaert's laboratory in Montpellier and managed a … WebAug 1, 2024 · The redistribution of the PIN3 proteins coincides with the lateral redistribution of auxin to the elongation zone in root gravitropic response. Further evidence of the role of PIN proteins in signal transduction arises with the evidence that PIN proteins cycle along the cell cytoskeleton between the endosome and the plant cytoskeleton [47].
WebMay 1, 2010 · PIN proteins are localized in plasma membrane in one side of cells, and this subcellular localization ensures directional polar auxin transport. The polar auxin transport is essential for normal shoot and root development in plants, since mutations in PIN genes result in abnormal shoot and root development.
WebAug 14, 2024 · Among the four rice PIN1 paralogous proteins, OsPIN1a and OsPIN1b were grouped into PIN1 group together with AtPIN1, BdPIN1a–b, GmPIN1a–c, PvPIN1a–c, SbPIN1a–b and ZmPIN1a–c, while OsPIN1c and OsPIN1d were grouped into SoPIN1 group with BdPIN1c, GmPIN1d–e, PvPIN1d, SbPIN1c and ZmPIN1d ( Supplementary Fig. S1 ). team build activitiesWeb2 days ago · A technique capable of identifying abnormal protein build-up linked to Parkinson's disease could allow early detection of the brain disorder and help in improved diagnosis and treatment, according to a study published April 13 (6:30 pm ET on April 12) in The Lancet Neurology journal.. The technique is known as α-synuclein seed and … team build activities corporateWebOct 12, 2009 · The PIN-FORMED (PIN) proteins are secondary transporters acting in the efflux of the plant signal molecule auxin from cells. They are asymmetrically localized … team build asiaWebJun 7, 2009 · PIN proteins are plant-specific integral membrane proteins directly involved in auxin efflux from cells 6, the asymmetric localization of which at the plasma membrane determines the... southwest behavioral health faxWebPIN1-catalyzed conformational regulation has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune … teambuild cetWebMay 12, 2006 · PIN and PGP proteins seem to have a comparable effect on mediating auxin efflux in yeast and HeLa cells, but the genetic interference with their function in … southwest behavioral health erickson clinicWebAug 1, 2024 · The unifying topology of all PIN proteins is a central hydrophilic loop of varying length, which is flanked by several, mostly conserved, N- and C-terminal … team build club