Tsc1 antibody

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August undefined, 2024

WebThis phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS312 of mouse TSC1. Storage. Aliquot the phospho-TSC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. WebHuman/Mouse/Rat TSC1 Antibody Summary. Detects human, mouse, and rat TSC1 in direct ELISAs and Western blots. Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

TSC1 - Antibodies - The Human Protein Atlas

WebProduct Description. Mouse anti Human TSC1 antibody recognizes TSC1, also known as hamartin and tuberous sclerosis 1 protein. TSC1 encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in TSC1 have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript ... WebFeb 3, 2024 · Double labeling with Tsc1 (Hamartin) and H +-ATPase antibodies demonstrated remarkable colocalization in cyst epithelial cells in Tsc1 KO mice (Fig. 3B). Double labeling with Tsc1 and AQP-2 antibodies indicated the expression of Tsc1 in the majority of cells lining the cysts with few and distinct AQP-2–expressing (principal cells … iran westernization

TSC1 antibody (ABIN1955081) - antibodies-online.com

WebTSC1 antibody (ABIN1955081). Validated for IHC, ELISA. Tested in Human. Order online. English ... Comparison List Basket Phone: +1 877 302 8632 Fax: +1 888 205 9894 (Toll-free) E-Mail: [email protected]. Home Antibodies ELISA Kits Primary Antibodies. Monoclonal Antibodies; Polyclonal Antibodies; Recombinant ... WebApr 11, 2024 · TSC1 and TSC2 are also involved in the G2/M transition of the cell cycle through their interactions with CDK1 and cyclin B1. TSC1 has also been shown to interact with Factin and ERM (EzrinRadixinMoesin) proteins, implying a role in the modulation of cell adhesion and morphology. Human TSC1 Antibody WebRabbit recombinant monoclonal mTOR (phospho S2448) antibody [EPR426(2)] - BSA and Azide free. Validated in WB, IHC, Dot and tested in Mouse, Human. iran what happened

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The tumor suppressor FLCN mediates an alternate mTOR pathway …

WebAntibodies that detect TSC1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Dot blot and ELISA. These antibodies … WebAntibody-bead conjugates were prepared by adding 2 µg of TSC1 monoclonal antibody ( Product # 37-0400) with 30 µL of protein G-Sepharose beads and rocked overnight at 4°C. … iran whatsappWebUrothelial carcinoma represents one of the most prevalent types of cancer worldwide, and its incidence is expected to grow. Although the treatment of the advanced disease was based on chemotherapy for decades, the developments of different therapies, such as immune checkpoint inhibitors, antibody drug conjugates and tyrosine kinase inhibitors, … iran what everyone needs to know

"WebEach TSC1 Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our TSC1 Antibodies can be used in a variety of model … " - Tsc1 antibody

Tsc1 antibody

Anti-TSC1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))

WebHerein, we show that a recombinant fusion protein of a humanized antibody to CD40 fused to HPV16.E6/7 (αCD40-HPV16.E6/7) can evoke HPV16.E6/7-specific CD8+ and CD4+ T-cell responses in head-and ... WebThis TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S505 of human TSC1. …

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WebImmunoprecipitation of TSC1 was performed on HAP1 cell lysates. Antibody-bead conjugates were prepared by adding 2 µg of TSC1 polyclonal antibody (Product # PA5 … WebThe regulation of the subcellular localization of phosphatase and tensin homologue (PTEN) is critical to its tumor-suppressing functions. Previously, we found that the activation of the phosphoinositide 3-kinase (PI3K)/Akt/mTOR/S6 protein kinase (S6K) cascade triggers the nuclear export of PTEN duri …

WebApr 14, 2024 · Phase III Abstracts presenting at AACR 2024. Drawing attention to the Phase II data readout, we have cancer vaccine players Moderna and Transgene excited about their personalized therapy.Merck is readily evaluating its flagship product as a combination in high-grade serous ovarian carcinoma, Aadi Biosciences heading towards grabbing a … WebAnti-TSC1 antibodies are offered by a number of suppliers. This target gene encodes the protein 'TSC complex subunit 1' in humans and may also be known as Hamartin, LAM, truncated hemartin, and tuberous sclerosis 1 protein. Structurally, the protein is reported to be 129.8 kilodaltons in mass. Based on gene name, fly, ...

WebMar 21, 2024 · TSC1 (TSC Complex Subunit 1) is a Protein Coding gene. Diseases associated with TSC1 include Tuberous Sclerosis 1 and Lymphangioleiomyomatosis . … WebInvitrogen Anti-TSC1 Polyclonal, Catalog # PA5-20130. Tested in Western Blot (WB) applications. This antibody reacts with Human, Mouse samples. Supplied as 100 µg …

WebMar 21, 2024 · In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, 28215400, 35772404).Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity …

WebAug 24, 2012 · The endogenous interaction of TBC1D7 with the TSC1-TSC2 complex was confirmed in reciprocal immunoprecipitations with a panel of six unique antibodies to TSC1 or TSC2, along with an antibody raised against TBC1D7 (Figure 1 B), the specificity of which was confirmed through siRNA-mediated knockdown of TBC1D7 (Figure S1 E).TBC1D7 … iran weeks away from nuclearWebMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val640 of human TSC1. Background Tuberous … iran what religionWebMonoclonal Antibody for studying Hamartin/TSC1. Cited in 10 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Hamartin/TSC1 (1B2) Mouse Monoclonal Antibody (CST #4963) is … iran what continentWebJan. 2024–Okt. 20242 Jahre 10 Monate. Lausanne Area, Switzerland. • Managing scientific, operations and budget of Preclinical Translational studies for small molecules (Therapeutic and Imaging projects) along with Antibody projects. • Designing, reviewing and executing preclinical investigation study protocols to close-out related activities. iran what\u0027s happeningWebFeb 25, 2024 · hamartin Antibody (C-8) is an IgG 2b κ mouse monoclonal hamartin antibody (also designated TSC1 antibody or TSC antibody) suitable for the detection of the hamartin protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. hamartin Antibody (C-8) is available as both the non-conjugated anti-hamartin antibody form, as well as … orden celestial genshinWebInvitrogen Anti-TSC1 Polyclonal, Catalog # PA5-20131. Tested in Western Blot (WB) and Immunocytochemistry (ICC/IF) applications. This antibody reacts with Human, Mouse, Rat … iran what time is itWeb5.2 TSC1–TSC2 complex. TSC1 and TSC2 genes were identified in 1997 and 1993 as the genetic loci mutated in the disease known as tuberous sclerosis complex (TSC) (European TSC Consortium, 1993; van Slegtenhorst et al., 1997). These genes’ products are two proteins, TSC1 and TSC2, which do not share any homology between them, and very little ... orden correcto para ver shingeki no kyojin